© 2023 National Autopsy Network

Publications

2023
1.
Azeke, A. T., Schädler, J., Ondruschka, B., Steurer, S., Möbius, D. & Fitzek, A. Minimally Invasive Tissue Sampling via Post Mortem Ultrasound: A Feasible Tool (Not Only) in Infectious Diseases-A Case Report. Diagnostics (Basel) 13, 2643 (2023).
1.
Woo, M. S., Shafiq, M., Fitzek, A., Dottermusch, M., Altmeppen, H., Mohammadi, B., Mayer, C., Bal, L. C., Raich, L., Matschke, J., Krasemann, S., Pfefferle, S., Brehm, T. T., Lütgehetmann, M., Schädler, J., Addo, M. M., Schulze zur Wiesch, J., Ondruschka, B., Friese, M. A. & Glatzel, M. Vagus nerve inflammation contributes to dysautonomia in COVID-19. Acta Neuropathol 146, 387–394 (2023).
1.
Stanelle-Bertram, S., Beck, S., Mounogou, N. K., Schaumburg, B., Stoll, F., Al Jawazneh, A., Schmal, Z., Bai, T., Zickler, M., Beythien, G., Becker, K., de la Roi, M., Heinrich, F., Schulz, C., Sauter, M., Krasemann, S., Lange, P., Heinemann, A., van Riel, D., Leijten, L., Bauer, L., van den Bosch, T. P. P., Lopuhaä, B., Busche, T., Wibberg, D., Schaudien, D., Goldmann, T., Lüttjohann, A., Ruschinski, J., Jania, H., Müller, Z., Pinho dos Reis, V., Krupp-Buzimkic, V., Wolff, M., Fallerini, C., Baldassarri, M., Furini, S., Norwood, K., Käufer, C., Schützenmeister, N., von Köckritz-Blickwede, M., Schroeder, M., Jarczak, D., Nierhaus, A., Welte, T., Kluge, S., McHardy, A. C., Sommer, F., Kalinowski, J., Krauss-Etschmann, S., Richter, F., von der Thüsen, J., Baumgärtner, W., Klingel, K., Ondruschka, B., Renieri, A. & Gabriel, G. CYP19A1 mediates severe SARS-CoV-2 disease outcome in males. Cell Reports Medicine 101152 (2023). http://doi.org/10.1016/j.xcrm.2023.101152
1.
Lücke, J., Heinrich, F., Malsy, J., Meins, N., Schnell, J., Böttcher, M., Nawrocki, M., Zhang, T., Bertram, F., Sabihi, M., Kempski, J., Blankenburg, T., Duprée, A., Reeh, M., Wolter, S., Mann, O., Izbicki, J. R., Lohse, A. W., Gagliani, N., Lütgehetmann, M., Bunders, M. J., Altfeld, M., Sauter, G., Giannou, A. D., Krasemann, S., Ondruschka, B. & Huber, S. Intestinal IL-1β Plays a Role in Protecting against SARS-CoV-2 Infection. The Journal of Immunology ji2200844 (2023). http://doi.org/10.4049/jimmunol.2200844
1.
Kolabas, Z. I., Kuemmerle, L. B., Perneczky, R., Förstera, B., Ulukaya, S., Ali, M., Kapoor, S., Bartos, L. M., Büttner, M., Caliskan, O. S., Rong, Z., Mai, H., Höher, L., Jeridi, D., Molbay, M., Khalin, I., Deligiannis, I. K., Negwer, M., Roberts, K., Simats, A., Carofiglio, O., Todorov, M. I., Horvath, I., Ozturk, F., Hummel, S., Biechele, G., Zatcepin, A., Unterrainer, M., Gnörich, J., Roodselaar, J., Shrouder, J., Khosravani, P., Tast, B., Richter, L., Díaz-Marugán, L., Kaltenecker, D., Lux, L., Chen, Y., Zhao, S., Rauchmann, B.-S., Sterr, M., Kunze, I., Stanic, K., Kan, V. W. Y., Besson-Girard, S., Katzdobler, S., Palleis, C., Schädler, J., Paetzold, J. C., Liebscher, S., Hauser, A. E., Gokce, O., Lickert, H., Steinke, H., Benakis, C., Braun, C., Martinez-Jimenez, C. P., Buerger, K., Albert, N. L., Höglinger, G., Levin, J., Haass, C., Kopczak, A., Dichgans, M., Havla, J., Kümpfel, T., Kerschensteiner, M., Schifferer, M., Simons, M., Liesz, A., Krahmer, N., Bayraktar, O. A., Franzmeier, N., Plesnila, N., Erener, S., Puelles, V. G., Delbridge, C., Bhatia, H. S., Hellal, F., Elsner, M., Bechmann, I., Ondruschka, B., Brendel, M., Theis, F. J. & Erturk, A. Distinct molecular profiles of skull bone marrow in health and neurological disorders. Cell S0092867423007420 (2023). http://doi.org/10.1016/j.cell.2023.07.009
1.
Mieling, R., Neidhardt, M., Latus, S., Stapper, C., Gerlach, S., Kniep, I., Heinemann, A., Ondruschka, B. & Schlaefer, A. Collaborative Robotic Biopsy with Trajectory Guidance and Needle Tip Force Feedback. in 2023 IEEE International Conference on Robotics and Automation (ICRA) 6893–6900 (2023). http://doi.org/10.1109/ICRA48891.2023.10161377
1.
Schädler, J., Lütgehetmann, M., Schröder, A. S., Edler, C., Püschel, K., Ondruschka, B. & Fitzek, A. Pilot study in Hamburg on the prevalence of SARS-CoV-2 infections and pandemic survey in the German funeral industry. Forensic Sci Med Pathol (2023). http://doi.org/10.1007/s12024-023-00661-y
1.
Aschman, T., Wyler, E., Baum, O., Hentschel, A., Legler, F., Preusse, C., Meyer-Arndt, L., Büttnerova, I., Förster, A., Cengiz, D., Alves, L. G. T., Schneider, J., Kedor, C., Rust, R., Bellmann-Strobl, J., Aminaa, S., Vajkoczy, P., Goebel, H.-H., Landthaler, M., Corman, V., Roos, A., Heppner, F. L., Radbruch, H., Paul, F., Scheibenbogen, C., Stenzel, W. & Dengler, N. F. Post-COVID syndrome is associated with capillary alterations, macrophage infiltration and distinct transcriptomic signatures in skeletal muscles. Preprint at https://doi.org/10.1101/2023.02.15.23285584 (2023)
1.
Gagiannis, D., Hackenbroch, C., Bloch, W., Zech, F., Kirchhoff, F., Djudjaj, S., von Stillfried, S., Bülow, R., Boor, P. & Steinestel, K. Clinical, Imaging, and Histopathological Features of Pulmonary Sequelae Following Mild COVID-19. Am J Respir Crit Care Med (2023). http://doi.org/10.1164/rccm.202302-0285LE
1.
Bräutigam, K., Reinhard, S., Wartenberg, M., Forster, S., Greif, K., Granai, M., Bösmüller, H., Klingel, K. & Schürch, C. M. Comprehensive analysis of SARS-CoV-2 receptor proteins in human respiratory tissues identifies alveolar macrophages as potential virus entry site. Histopathology 82, 846–859 (2023).
1.
Granai, M., Warm, V., Vogelsberg, A., Milla, J., Greif, K., Vogel, U., Bakchoul, T., Rosenberger, P., Quintanilla-Martinez, L., Schürch, C., Klingel, K., Fend, F. & Bösmüller, H. Impact of P-selectin-PSGL-1 Axis on Platelet-Endothelium-Leucocyte Interactions in Fatal COVID-19. Lab Invest 100179 (2023). http://doi.org/10.1016/j.labinv.2023.100179
1.
Heinrich, F., Huter, T., Mertens, S., Lange, P., Vering, J., Heinemann, A., Nörz, D. S., Hoffmann, A., Aepfelbacher, M., Ondruschka, B., Krasemann, S. & Lütgehetmann, M. New Postmortem Perspective on Emerging SARS-CoV-2 Variants of Concern, Germany. Emerg Infect Dis 29, 652–656 (2023).
1.
Lücke, J., Nawrocki, M., Schnell, J., Meins, N., Heinrich, F., Zhang, T., Bertram, F., Sabihi, M., Böttcher, M., Blankenburg, T., Pfaff, M., Notz, S., Kempski, J., Reeh, M., Wolter, S., Mann, O., Izbicki, J. R., Lütgehetmann, M., Duprée, A., Giannou, A. D., Ondruschka, B. & Huber, S. TNFα aggravates detrimental effects of SARS-CoV-2 infection in the liver. Front Immunol 14, 1151937 (2023).
2022
1.
Gaede, K., Heidemann, J., Goebels, H.-L., Heinemann, A., Püschel, K. & Ondruschka, B. Pandemic Preparedness bei der Obduktion? Potentiale und Grenzen des IfSG. MedR 40, 892–901 (2022).
1.
Paparoupa, M., Schröder, A. S., Braunsteiner, J., Addo, M. M., Lütgehetmann, M., Roedl, K., Kluge, S., Ondruschka, B. & Wichmann, D. The Effects of SARS-CoV-2 Virus Type and of Vaccination Status on Causes of Death Over the Course of the COVID-19 Pandemic. Dtsch Arztebl Int 607–608 (2022). at <https://dx.doi.org/10.3238/arztebl.m2022.0255>
1.
Ackermann, M. & Jonigk, D. D. Microvascular placental alterations in maternal COVID-19. Am J Obstet Gynecol 226, 135–136 (2022).
1.
Ackermann, M., Tafforeau, P., Wagner, W. L., Walsh, C. L., Werlein, C., Kühnel, M. P., Länger, F. P., Disney, C., Bodey, A. J., Bellier, A., Verleden, S. E., Lee, P. D., Mentzer, S. J. & Jonigk, D. D. The Bronchial Circulation in COVID-19 Pneumonia. Am J Respir Crit Care Med 205, 121–125 (2022).
1.
Ameratunga, R., Woon, S.-T., Sheppard, M. N., Garland, J., Ondruschka, B., Wong, C. X., Stewart, R. A. H., Tatley, M., Stables, S. R. & Tse, R. D. First Identified Case of Fatal Fulminant Necrotizing Eosinophilic Myocarditis Following the Initial Dose of the Pfizer-BioNTech mRNA COVID-19 Vaccine (BNT162b2, Comirnaty): an Extremely Rare Idiosyncratic Hypersensitivity Reaction. J Clin Immunol 42, 441–447 (2022).
1.
Aschman, T., Mothes, R., Heppner, F. L. & Radbruch, H. What SARS-CoV-2 does to our brains. Immunity 55, 1159–1172 (2022).
1.
Brandner, J. M., Boor, P., Borcherding, L., Edler, C., Gerber, S., Heinemann, A., Hilsenbeck, J., Kasajima, A., Lohner, L., Märkl, B., Pablik, J., Schröder, A. S., Slotta-Huspenina, J., Sommer, L., Sperhake, J.-P., von Stillfried, S. & Dintner, S. Contamination of personal protective equipment during COVID-19 autopsies. Virchows Arch 480, 519–528 (2022).
1.
Bräuninger, H., Stoffers, B., Fitzek, A. D. E., Meißner, K., Aleshcheva, G., Schweizer, M., Weimann, J., Rotter, B., Warnke, S., Edler, C., Braun, F., Roedl, K., Scherschel, K., Escher, F., Kluge, S., Huber, T. B., Ondruschka, B., Schultheiss, H.-P., Kirchhof, P., Blankenberg, S., Püschel, K., Westermann, D. & Lindner, D. Cardiac SARS-CoV-2 infection is associated with pro-inflammatory transcriptomic alterations within the heart. Cardiovasc Res 118, 542–555 (2022).
1.
Casagrande, M., Fitzek, A., Spitzer, M., Püschel, K., Glatzel, M., Krasemann, S., Aepfelbacher, M., Nörz, D., Lütgehetmann, M., Pfefferle, S. & Schultheiss, M. Detection of SARS-CoV-2 genomic and subgenomic RNA in retina and optic nerve of patients with COVID-19. Br J Ophthalmol 106, 1313–1317 (2022).
1.
Georg, P., Astaburuaga-García, R., Bonaguro, L., Brumhard, S., Michalick, L., Lippert, L. J., Kostevc, T., Gäbel, C., Schneider, M., Streitz, M., Demichev, V., Gemünd, I., Barone, M., Tober-Lau, P., Helbig, E. T., Hillus, D., Petrov, L., Stein, J., Dey, H.-P., Paclik, D., Iwert, C., Mülleder, M., Aulakh, S. K., Djudjaj, S., Bülow, R. D., Mei, H. E., Schulz, A. R., Thiel, A., Hippenstiel, S., Saliba, A.-E., Eils, R., Lehmann, I., Mall, M. A., Stricker, S., Röhmel, J., Corman, V. M., Beule, D., Wyler, E., Landthaler, M., Obermayer, B., von Stillfried, S., Boor, P., Demir, M., Wesselmann, H., Suttorp, N., Uhrig, A., Müller-Redetzky, H., Nattermann, J., Kuebler, W. M., Meisel, C., Ralser, M., Schultze, J. L., Aschenbrenner, A. C., Thibeault, C., Kurth, F., Sander, L. E., Blüthgen, N., Sawitzki, B. & PA-COVID-19 Study Group. Complement activation induces excessive T cell cytotoxicity in severe COVID-19. Cell 185, 493-512.e25 (2022).
1.
Heinrich, F., Roedl, K., Jarczak, D., Goebels, H.-L., Heinemann, A., Schäfer, U., Ludwig, F., Bachmann, M., Bein, B., Weber, C. F., Sydow, K., Bota, M., Paschen, H.-R., de Weerth, A., Veit, C., Detsch, O., Brand, P.-A., Kluge, S., Ondruschka, B. & Wichmann, D. New Insights in the Occurrence of Venous Thromboembolism in Critically Ill Patients with COVID-19-A Large Postmortem and Clinical Analysis. Viruses 14, 811 (2022).
1.
Gagiannis, D., Umathum, V. G., Bloch, W., Rother, C., Stahl, M., Witte, H. M., Djudjaj, S., Boor, P. & Steinestel, K. Antemortem vs Postmortem Histopathologic and Ultrastructural Findings in Paired Transbronchial Biopsy Specimens and Lung Autopsy Samples From Three Patients With Confirmed SARS-CoV-2. American Journal of Clinical Pathology 157, 54–63 (2022).
1.
Hirschbühl, K., Schaller, T., Märkl, B., Claus, R., Sipos, E., Rentschler, L., Maccagno, A., Grosser, B., Kling, E., Neidig, M., Kröncke, T., Spring, O., Braun, G., Bösmüller, H., Seidl, M., Esposito, I., Pablik, J., Hilsenbeck, J., Boor, P., Beer, M., Dintner, S. & Wylezich, C. High viral loads: what drives fatal cases of COVID-19 in vaccinees? – an autopsy study. Mod Pathol 35, 1013–1021 (2022).
1.
Neidhardt, M., Gerlach, S., Mieling, R., Laves, M.-H., Weiß, T., Gromniak, M., Fitzek, A., Möbius, D., Kniep, I., Ron, A., Schädler, J., Heinemann, A., Püschel, K., Ondruschka, B. & Schlaefer, A. Robotic Tissue Sampling for Safe Post-Mortem Biopsy in Infectious Corpses. IEEE Transactions on Medical Robotics and Bionics 4, 94–105 (2022).
1.
Heinrich, F., Romich, C., Zimmermann, T., Kniep, I., Fitzek, A., Steurer, S., Glatzel, M., Nörz, D., Günther, T., Czech-Sioli, M., Fischer, N., Grundhoff, A., Lütgehetmann, M. & Ondruschka, B. Dying of VOC-202012/01 — multimodal investigations in a death case of the SARS-CoV-2 variant. Int J Legal Med 136, 193–202 (2022).
1.
Heinrich, F., Schröder, A. S., Gerberding, A.-L., Gerling, M., Langenwalder, F., Lange, P., Heinemann, A., Bibiza-Freiwald, E., Nörz, D. S., Aepfelbacher, M., Pfefferle, S., Ondruschka, B. & Lütgehetmann, M. Postmortem Antigen-Detecting Rapid Diagnostic Tests to Predict Infectivity of SARS-CoV-2-Associated Deaths. Emerg Infect Dis 28, 244–247 (2022).
1.
Jansen, J., Reimer, K. C., Nagai, J. S., Varghese, F. S., Overheul, G. J., de Beer, M., Roverts, R., Daviran, D., Fermin, L. A. S., Willemsen, B., Beukenboom, M., Djudjaj, S., von Stillfried, S., van Eijk, L. E., Mastik, M., Bulthuis, M., Dunnen, W. den, van Goor, H., Hillebrands, J.-L., Triana, S. H., Alexandrov, T., Timm, M.-C., van den Berge, B. T., van den Broek, M., Nlandu, Q., Heijnert, J., Bindels, E. M. J., Hoogenboezem, R. M., Mooren, F., Kuppe, C., Miesen, P., Grünberg, K., Ijzermans, T., Steenbergen, E. J., Czogalla, J., Schreuder, M. F., Sommerdijk, N., Akiva, A., Boor, P., Puelles, V. G., Floege, J., Huber, T. B., COVID Moonshot consortium, van Rij, R. P., Costa, I. G., Schneider, R. K., Smeets, B. & Kramann, R. SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids. Cell Stem Cell 29, 217-231.e8 (2022).
1.
Jonigk, D., Werlein, C., Acker, T., Aepfelbacher, M., Amann, K. U., Baretton, G., Barth, P., Bohle, R. M., Büttner, A., Büttner, R., Dettmeyer, R., Eichhorn, P., Elezkurtaj, S., Esposito, I., Evert, K., Evert, M., Fend, F., Gaßler, N., Gattenlöhner, S., Glatzel, M., Göbel, H., Gradhand, E., Hansen, T., Hartmann, A., Heinemann, A., Heppner, F. L., Hilsenbeck, J., Horst, D., Kamp, J. C., Mall, G., Märkl, B., Ondruschka, B., Pablik, J., Pfefferle, S., Quaas, A., Radbruch, H., Röcken, C., Rosenwald, A., Roth, W., Rudelius, M., Schirmacher, P., Slotta-Huspenina, J., Smith, K., Sommer, L., Stock, K., Ströbel, P., Strobl, S., Titze, U., Weirich, G., Weis, J., Werner, M., Wickenhauser, C., Wiech, T., Wild, P., Welte, T., von Stillfried, S. & Boor, P. Organ manifestations of COVID-19: what have we learned so far (not only) from autopsies? Virchows Arch 481, 139–159 (2022).
1.
Kamp, J. C., Neubert, L., Ackermann, M., Stark, H., Werlein, C., Fuge, J., Haverich, A., Tzankov, A., Steinestel, K., Friemann, J., Boor, P., Junker, K., Hoeper, M. M., Welte, T., Laenger, F., Kuehnel, M. P. & Jonigk, D. D. Time-Dependent Molecular Motifs of Pulmonary Fibrogenesis in COVID-19. Int J Mol Sci 23, 1583 (2022).
1.
Krasemann, S., Dittmayer, C., von Stillfried, S., Meinhardt, J., Heinrich, F., Hartmann, K., Pfefferle, S., Thies, E., von Manitius, R., Aschman, T. A. D., Radke, J., Osterloh, A., Schmid, S., Buhl, E. M., Ihlow, J., Dubois, F., Arnhold, V., Elezkurtaj, S., Horst, D., Hocke, A., Timm, S., Bachmann, S., Corman, V., Goebel, H.-H., Matschke, J., Stanelle-Bertram, S., Gabriel, G., Seilhean, D., Adle-Biassette, H., Ondruschka, B., Ochs, M., Stenzel, W., Heppner, F. L., Boor, P., Radbruch, H., Laue, M. & Glatzel, M. Assessing and improving the validity of COVID-19 autopsy studies – A multicentre approach to establish essential standards for immunohistochemical and ultrastructural analyses. EBioMedicine 83, 104193 (2022).
1.
Pomara, C., Salerno, M., Miani, A. & Piscitelli, P. Autopsies in COVID-related deaths: The need for following the model of German COVID-19 autopsy registry. Lancet Reg Health Eur 17, 100392 (2022).
1.
von Stillfried, S., Bülow, R. D., Röhrig, R., Boor, P. & German Registry of COVID-19 Autopsies (DeRegCOVID), DeRegCOVID Collaborators. First report from the German COVID-19 autopsy registry. Lancet Reg Health Eur 15, 100330 (2022).
1.
von Stillfried, S., Bülow, R. D., Röhrig, R., Meybohm, P., Boor, P. & German Registry of COVID-19 Autopsies (DeRegCOVID), DeRegCOVID Collaborators#. Intracranial hemorrhage in COVID-19 patients during extracorporeal membrane oxygenation for acute respiratory failure: a nationwide register study report. Crit Care 26, 83 (2022).
1.
von Stillfried, S., Freeborn, B., Windeck, S. & Boor, P. Update zur kooperativen autopsiebasierten Forschung in der deutschen Pathologie, Neuropathologie und Gerichtsmedizin. Pathologie (Heidelb) 43, 101–105 (2022).
1.
Voigtlaender, M., Edler, C., Gerling, M., Schädler, J., Ondruschka, B., Schröder, A. S., Sperhake, J., Ehrhardt, S., Wang, L., Haddad, M., Kiencke, V., Renné, T., Roedl, K., Kluge, S., Wichmann, D. & Langer, F. Thromboembolic events in deceased patients with proven SARS-CoV-2 infection: Frequency, characteristics and risk factors. Thromb Res 218, 171–176 (2022).
1.
Zickler, M., Stanelle-Bertram, S., Ehret, S., Heinrich, F., Lange, P., Schaumburg, B., Kouassi, N. M., Beck, S., Jaeckstein, M. Y., Mann, O., Krasemann, S., Schroeder, M., Jarczak, D., Nierhaus, A., Kluge, S., Peschka, M., Schlüter, H., Renné, T., Pueschel, K., Kloetgen, A., Scheja, L., Ondruschka, B., Heeren, J. & Gabriel, G. Replication of SARS-CoV-2 in adipose tissue determines organ and systemic lipid metabolism in hamsters and humans. Cell Metab 34, 1–2 (2022).
1.
Wanner, N., Andrieux, G., Badia-I-Mompel, P., Edler, C., Pfefferle, S., Lindenmeyer, M. T., Schmidt-Lauber, C., Czogalla, J., Wong, M. N., Okabayashi, Y., Braun, F., Lütgehetmann, M., Meister, E., Lu, S., Noriega, M. L. M., Günther, T., Grundhoff, A., Fischer, N., Bräuninger, H., Lindner, D., Westermann, D., Haas, F., Roedl, K., Kluge, S., Addo, M. M., Huber, S., Lohse, A. W., Reiser, J., Ondruschka, B., Sperhake, J. P., Saez-Rodriguez, J., Boerries, M., Hayek, S. S., Aepfelbacher, M., Scaturro, P., Puelles, V. G. & Huber, T. B. Molecular consequences of SARS-CoV-2 liver tropism. Nat Metab 4, 310–319 (2022).
2021
1.
Reichardt, M., Moller Jensen, P., Andersen Dahl, V., Bjorholm Dahl, A., Ackermann, M., Shah, H., Länger, F., Werlein, C., Kuehnel, M. P., Jonigk, D. & Salditt, T. 3D virtual histopathology of cardiac tissue from Covid-19 patients based on phase-contrast X-ray tomography. eLife 10, e71359 (2021).
1.
Heinrich, F., Meißner, K., Langenwalder, F., Püschel, K., Nörz, D., Hoffmann, A., Lütgehetmann, M., Aepfelbacher, M., Bibiza-Freiwald, E., Pfefferle, S. & Heinemann, A. Postmortem Stability of SARS-CoV-2 in Nasopharyngeal Mucosa – Volume 27, Number 1—January 2021 – Emerging Infectious Diseases journal – CDC. (2021). http://doi.org/10.3201/eid2701.203112
1.
Zack, F., Nigbur, S., Derani, H., Boy, D., Port, A. & Büttner, A. Erste Ergebnisse der Obduktionen der im Zusammenhang mit den SARS-CoV-2-Infektionen Verstorbenen aus der Unimedizin Rostock. Ärztebl Meckl-Vorpom 31, 125–128 (2021).
1.
Verhoff, M., Püschel, K. & Ondruschka, B. SARS-CoV-2: Was bei der Leichenschau infizierter Verstorbener zu beachten ist. MMW Fortschr Med 56–58 (2021). at <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8214379/>
1.
Püschel, K., Goebels, H., Ondruschka, B., Heinrich, F., Bräuninger, H., Lindner, D. & Westermann, D. Kardiopathologische Befunde bei COVID-19-Sterbefällen. (2021). at <https://www.uke.de/dateien/einrichtungen/medizinische-fakult%C3%A4t/forschung/hzm_01_2021_kardiopathologie_1.pdf>
1.
Wendisch, D., Dietrich, O., Mari, T., von Stillfried, S., Ibarra, I. L., Mittermaier, M., Mache, C., Chua, R. L., Knoll, R., Timm, S., Brumhard, S., Krammer, T., Zauber, H., Hiller, A. L., Pascual-Reguant, A., Mothes, R., Bülow, R. D., Schulze, J., Leipold, A. M., Djudjaj, S., Erhard, F., Geffers, R., Pott, F., Kazmierski, J., Radke, J., Pergantis, P., Baßler, K., Conrad, C., Aschenbrenner, A. C., Sawitzki, B., Landthaler, M., Wyler, E., Horst, D., Deutsche COVID-19 OMICS Initiative (DeCOI), Hippenstiel, S., Hocke, A., Heppner, F. L., Uhrig, A., Garcia, C., Machleidt, F., Herold, S., Elezkurtaj, S., Thibeault, C., Witzenrath, M., Cochain, C., Suttorp, N., Drosten, C., Goffinet, C., Kurth, F., Schultze, J. L., Radbruch, H., Ochs, M., Eils, R., Müller-Redetzky, H., Hauser, A. E., Luecken, M. D., Theis, F. J., Conrad, C., Wolff, T., Boor, P., Selbach, M., Saliba, A.-E. & Sander, L. E. SARS-CoV-2 infection triggers profibrotic macrophage responses and lung fibrosis. Cell 184, 6243-6261.e27 (2021).
1.
Walsh, C. L., Tafforeau, P., Wagner, W. L., Jafree, D. J., Bellier, A., Werlein, C., Kühnel, M. P., Boller, E., Walker-Samuel, S., Robertus, J. L., Long, D. A., Jacob, J., Marussi, S., Brown, E., Holroyd, N., Jonigk, D. D., Ackermann, M. & Lee, P. D. Imaging intact human organs with local resolution of cellular structures using hierarchical phase-contrast tomography. Nat Methods 18, 1532–1541 (2021).
1.
van Rüth, V., König, H.-H., Bertram, F., Schmiedel, P., Ondruschka, B., Püschel, K., Heinrich, F. & Hajek, A. Determinants of health-related quality of life among homeless individuals during the COVID-19 pandemic. Public Health 194, 60–66 (2021).
1.
Verhoff, M., Püschel, K. & Ondruschka, B. Über die Ansteckungsgefahr beim Umgang mit SARS-CoV-2-positiven Leichen. Bestattungskultur 24–28 (2021). at <https://fis-uke.de/portal/de/publications/uber-die-ansteckungsgefahr-beim-umgang-mit-sarscov2positiven-leichen(a5affc27-e329-4aa4-8a39-566dbe2728c7).html>
1.
Witkowski, M., Tizian, C., Ferreira-Gomes, M., Niemeyer, D., Jones, T. C., Heinrich, F., Frischbutter, S., Angermair, S., Hohnstein, T., Mattiola, I., Nawrath, P., McEwen, S., Zocche, S., Viviano, E., Heinz, G. A., Maurer, M., Kölsch, U., Chua, R. L., Aschman, T., Meisel, C., Radke, J., Sawitzki, B., Roehmel, J., Allers, K., Moos, V., Schneider, T., Hanitsch, L., Mall, M. A., Conrad, C., Radbruch, H., Duerr, C. U., Trapani, J. A., Marcenaro, E., Kallinich, T., Corman, V. M., Kurth, F., Sander, L. E., Drosten, C., Treskatsch, S., Durek, P., Kruglov, A., Radbruch, A., Mashreghi, M.-F. & Diefenbach, A. Untimely TGFβ responses in COVID-19 limit antiviral functions of NK cells. Nature 600, 295–301 (2021).
1.
von Stillfried, S., Boor, P. & DeRegCOVID und DEFEAT PANDEMIcs. Entwicklung eines kooperativen Obduktionsnetzwerks aus Pathologie, Neuropathologie und Rechtsmedizin. Pathologe 42, 129–134 (2021).
1.
Wenzel, J., Lampe, J., Müller-Fielitz, H., Schuster, R., Zille, M., Müller, K., Krohn, M., Körbelin, J., Zhang, L., Özorhan, Ü., Neve, V., Wagner, J. U. G., Bojkova, D., Shumliakivska, M., Jiang, Y., Fähnrich, A., Ott, F., Sencio, V., Robil, C., Pfefferle, S., Sauve, F., Coêlho, C. F. F., Franz, J., Spiecker, F., Lembrich, B., Binder, S., Feller, N., König, P., Busch, H., Collin, L., Villaseñor, R., Jöhren, O., Altmeppen, H. C., Pasparakis, M., Dimmeler, S., Cinatl, J., Püschel, K., Zelic, M., Ofengeim, D., Stadelmann, C., Trottein, F., Nogueiras, R., Hilgenfeld, R., Glatzel, M., Prevot, V. & Schwaninger, M. The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells. Nat Neurosci 24, 1522–1533 (2021).
1.
Heinrich, F., Nentwich, M. F., Bibiza-Freiwald, E., Nörz, D., Roedl, K., Christner, M., Hoffmann, A., Olearo, F., Kluge, S., Aepfelbacher, M., Wichmann, D., Lütgehetmann, M. & Pfefferle, S. SARS-CoV-2 Blood RNA Load Predicts Outcome in Critically Ill COVID-19 Patients. Open Forum Infectious Diseases 8, ofab509 (2021).
1.
Ondruschka, B., Püschel, K., Lange, P., Becker, I., Rieger-Ndakorerwa, G. & Schröder, A. S. SARS-CoV-2-assoziierte Hamburger Sterbefälle in der zweiten Pandemiewelle – Vergleich der bekannt gewordenen Todesfälle in den Gesundheitsämtern und der Rechtsmedizin. Archiv für Kriminologie 248, 180–187 (2021).
1.
Michel, P., Savinsky, G., Ondruschka, B. & Czinczoll, I. Folgen einer Reanimation in Zeiten der Pandemie. Hamburger Ärzteblatt 2021, 28–30 (2021).
1.
Nörz, D., Grunwald, M., Olearo, F., Fischer, N., Aepfelbacher, M., Pfefferle, S. & Lütgehetmann, M. Evaluation of a fully automated high-throughput SARS-CoV-2 multiplex qPCR assay with built-in screening functionality for del-HV69/70- and N501Y variants such as B.1.1.7. Journal of Clinical Virology 141, 104894 (2021).
1.
Simnica, D., Schultheiß, C., Mohme, M., Paschold, L., Willscher, E., Fitzek, A., Püschel, K., Matschke, J., Ciesek, S., Sedding, D. G., Zhao, Y., Gagliani, N., Maringer, Y., Walz, J. S., Heide, J., Schulze-zur-Wiesch, J. & Binder, M. Landscape of T-cell repertoires with public COVID-19-associated T-cell receptors in pre-pandemic risk cohorts. Clinical & Translational Immunology 10, e1340 (2021).
1.
Berezowska, S., Boor, P., Jonigk, D. & Tischler, V. Update Thoraxpathologie 2021 – Bericht der Arbeitsgemeinschaft. Pathologe 42, 199–202 (2021).
1.
Lehmann, M., Allers, K., Heldt, C., Meinhardt, J., Schmidt, F., Rodriguez-Sillke, Y., Kunkel, D., Schumann, M., Böttcher, C., Stahl-Hennig, C., Elezkurtaj, S., Bojarski, C., Radbruch, H., Corman, V. M., Schneider, T., Loddenkemper, C., Moos, V., Weidinger, C., Kühl, A. A. & Siegmund, B. Human small intestinal infection by SARS-CoV-2 is characterized by a mucosal infiltration with activated CD8+ T cells. Mucosal Immunology 14, 1381–1392 (2021).
1.
Menger, J., Apostolidou, S., Edler, C., Kniep, I., Kobbe, R., Singer, D. & Sperhake, J.-P. Fatal outcome of SARS-CoV-2 infection (B1.1.7) in a 4-year-old child. Int J Legal Med 136, 189–192 (2022).
1.
Schwabenland, M., Salié, H., Tanevski, J., Killmer, S., Lago, M. S., Schlaak, A. E., Mayer, L., Matschke, J., Püschel, K., Fitzek, A., Ondruschka, B., Mei, H. E., Boettler, T., Neumann-Haefelin, C., Hofmann, M., Breithaupt, A., Genc, N., Stadelmann, C., Saez-Rodriguez, J., Bronsert, P., Knobeloch, K.-P., Blank, T., Thimme, R., Glatzel, M., Prinz, M. & Bengsch, B. Deep spatial profiling of human COVID-19 brains reveals neuroinflammation with distinct microanatomical microglia-T-cell interactions. Immunity 54, 1594-1610.e11 (2021).
1.
Edler, C., Klein, A., Schröder, A. S., Sperhake, J.-P. & Ondruschka, B. Deaths associated with newly launched SARS-CoV-2 vaccination (Comirnaty®). Legal Medicine 51, 101895 (2021).
1.
Gerlach, S., Neidhardt, M., Weiß, T., Laves, M.-H., Stapper, C., Gromniak, M., Kniep, I., Möbius, D., Heinemann, A., Ondruschka, B. & Schlaefer, A. Needle insertion planning for obstacle avoidance in robotic biopsy. Current Directions in Biomedical Engineering 7, 779–782 (2021).
1.
Elezkurtaj, S., Greuel, S., Ihlow, J., Michaelis, E. G., Bischoff, P., Kunze, C. A., Sinn, B. V., Gerhold, M., Hauptmann, K., Ingold-Heppner, B., Miller, F., Herbst, H., Corman, V. M., Martin, H., Radbruch, H., Heppner, F. L. & Horst, D. Causes of death and comorbidities in hospitalized patients with COVID-19. Sci Rep 11, 4263 (2021).
1.
O’Hare, M., Amarnani, D., Whitmore, H. A. B., An, M., Marino, C., Ramos, L., Delgado-Tirado, S., Hu, X., Chmielewska, N., Chandrahas, A., Fitzek, A., Heinrich, F., Steurer, S., Ondruschka, B., Glatzel, M., Krasemann, S., Sepulveda-Falla, D., Lagares, D., Pedron, J., Bushweller, J. H., Liu, P., Arboleda-Velasquez, J. F. & Kim, L. A. Targeting Runt-Related Transcription Factor 1 Prevents Pulmonary Fibrosis and Reduces Expression of Severe Acute Respiratory Syndrome Coronavirus 2 Host Mediators. The American Journal of Pathology 191, 1193–1208 (2021).
1.
Gromniak, M., Neidhardt, M., Heinemann, A., Püschel, K. & Schlaefer, A. Needle placement accuracy in CT-guided robotic post mortem biopsy. Current Directions in Biomedical Engineering 6, (2020).
1.
Aschman, T., Schneider, J., Greuel, S., Meinhardt, J., Streit, S., Goebel, H.-H., Büttnerova, I., Elezkurtaj, S., Scheibe, F., Radke, J., Meisel, C., Drosten, C., Radbruch, H., Heppner, F. L., Corman, V. M. & Stenzel, W. Association Between SARS-CoV-2 Infection and Immune-Mediated Myopathy in Patients Who Have Died. JAMA Neurology 78, 948–960 (2021).
1.
Kruse, J. M., Zickler, D., Lüdemann, W. M., Piper, S. K., Gotthardt, I., Ihlow, J., Greuel, S., Horst, D., Kahl, A., Eckardt, K.-U. & Elezkurtaj, S. Evidence for a thromboembolic pathogenesis of lung cavitations in severely ill COVID-19 patients. Sci Rep 11, 16039 (2021).
1.
Dittmayer, C., Meinhardt, J., Radbruch, H., Radke, J., Heppner, B. I., Heppner, F. L., Stenzel, W., Holland, G. & Laue, M. Using EM data to understand COVID-19 pathophysiology – Authors’ reply. The Lancet 397, 197–198 (2021).
1.
Ihlow, J., Michaelis, E., Greuel, S., Heynol, V., Lehmann, A., Radbruch, H., Meinhardt, J., Miller, F., Herbst, H., Corman, V. M., Westermann, J., Bullinger, L., Horst, D., von Brünneck, A.-C. & Elezkurtaj, S. B cell depletion and signs of sepsis-acquired immunodeficiency in bone marrow and spleen of COVID-19 deceased. International Journal of Infectious Diseases 103, 628–635 (2021).
1.
Greuel, S., Ihlow, J., Dragomir, M.-P., Streit, S., Corman, V. M., Haberbosch, L., Winkler, D., Meinhardt, J., Aschman, T., Schneider, J., Trotsyuk, I., Kunze, C. A., Maurer, L., Radbruch, H., Heppner, F. L., Horst, D. & Elezkurtaj, S. COVID-19: Autopsy findings in six patients between 26 and 46 years of age. International Journal of Infectious Diseases 108, 274–281 (2021).
1.
Ihlow, J., Seelhoff, A., Corman, V. M., Gruber, A. D., Dökel, S., Meinhardt, J., Radbruch, H., Späth-Schwalbe, E., Elezkurtaj, S., Horst, D. & Herbst, H. COVID-19: a fatal case of acute liver failure associated with SARS-CoV-2 infection in pre-existing liver cirrhosis. BMC Infectious Diseases 21, 901 (2021).
1.
Fitzek, A., Schädler, J., Dietz, E., Ron, A., Gerling, M., Kammal, A. L., Lohner, L., Falck, C., Möbius, D., Goebels, H., Gerberding, A.-L., Schröder, A. S., Sperhake, J.-P., Klein, A., Fröb, D., Mushumba, H., Wilmes, S., Anders, S., Kniep, I., Heinrich, F., Langenwalder, F., Meißner, K., Lange, P., Zapf, A., Püschel, K., Heinemann, A., Glatzel, M., Matschke, J., Aepfelbacher, M., Lütgehetmann, M., Steurer, S., Thorns, C., Edler, C. & Ondruschka, B. Prospective postmortem evaluation of 735 consecutive SARS-CoV-2-associated death cases. Sci Rep 11, 19342 (2021).
1.
Swoboda, J., Wittschieber, D., Sanft, J., Kleemann, S., Elschner, S., Ihle, H., Hubig, M., Pletz, M. W., Mall, G. & Gassler, N. Bone marrow haemophagocytosis indicates severe infection with severe acute respiratory syndrome coronavirus 2. Histopathology 78, 727–737 (2021).
1.
Kaltschmidt, B., Fitzek, A. D. E., Schaedler, J., Förster, C., Kaltschmidt, C., Hansen, T., Steinfurth, F., Windmöller, B. A., Pilger, C., Kong, C., Singh, K., Nierhaus, A., Wichmann, D., Sperhake, J., Püschel, K., Huser, T., Krüger, M., Robson, S. C., Wilkens, L. & Schulte am Esch, J. Hepatic Vasculopathy and Regenerative Responses of the Liver in Fatal Cases of COVID-19. Clinical Gastroenterology and Hepatology 19, 1726-1729.e3 (2021).
1.
Kahn, M., Schuierer, L., Bartenschlager, C., Zellmer, S., Frey, R., Freitag, M., Dhillon, C., Heier, M., Ebigbo, A., Denzel, C., Temizel, S., Messmann, H., Wehler, M., Hoffmann, R., Kling, E. & Römmele, C. Performance of antigen testing for diagnosis of COVID-19: a direct comparison of a lateral flow device to nucleic acid amplification based tests. BMC Infectious Diseases 21, 798 (2021).
1.
Smadja, D. M., Mentzer, S. J., Fontenay, M., Laffan, M. A., Ackermann, M., Helms, J., Jonigk, D., Chocron, R., Pier, G. B., Gendron, N., Pons, S., Diehl, J.-L., Margadant, C., Guerin, C., Huijbers, E. J. M., Philippe, A., Chapuis, N., Nowak-Sliwinska, P., Karagiannidis, C., Sanchez, O., Kümpers, P., Skurnik, D., Randi, A. M. & Griffioen, A. W. COVID-19 is a systemic vascular hemopathy: insight for mechanistic and clinical aspects. Angiogenesis 24, 755–788 (2021).
1.
Rank, A., Tzortzini, A., Kling, E., Schmid, C., Claus, R., Löll, E., Burger, R., Römmele, C., Dhillon, C., Müller, K., Girl, P., Hoffmann, R., Grützner, S. & Dennehy, K. M. One Year after Mild COVID-19: The Majority of Patients Maintain Specific Immunity, But One in Four Still Suffer from Long-Term Symptoms. Journal of Clinical Medicine 10, 3305 (2021).
1.
Ricke-Hoch, M., Stelling, E., Lasswitz, L., Gunesch, A. P., Kasten, M., Zapatero-Belinchón, F. J., Brogden, G., Gerold, G., Pietschmann, T., Montiel, V., Balligand, J.-L., Facciotti, F., Hirsch, E., Gausepohl, T., Elbahesh, H., Rimmelzwaan, G. F., Höfer, A., Kühnel, M. P., Jonigk, D., Eigendorf, J., Tegtbur, U., Mink, L., Scherr, M., Illig, T., Schambach, A., Pfeffer, T. J., Hilfiker, A., Haverich, A. & Hilfiker-Kleiner, D. Impaired immune response mediated by prostaglandin E2 promotes severe COVID-19 disease. PLOS ONE 16, e0255335 (2021).
1.
Hansen, T., Titze, U., Kulamadayil-Heidenreich, N. S. A., Glombitza, S., Tebbe, J. J., Röcken, C., Schulz, B., Weise, M. & Wilkens, L. First case of postmortem study in a patient vaccinated against SARS-CoV-2. International Journal of Infectious Diseases 107, 172–175 (2021).
1.
Ondruschka, B., Heinrich, F., Lindenmeyer, M., Edler, C., Möbius, D., Czogalla, J., Heinemann, A., Braun, F., Aepfelbacher, M., Lütgehetmann, M. & Huber, T. B. Multiorgan tropism of SARS-CoV-2 lineage B.1.1.7. Int J Legal Med 135, 2347–2349 (2021).
1.
Wong, D. W. L., Klinkhammer, B. M., Djudjaj, S., Villwock, S., Timm, M. C., Buhl, E. M., Wucherpfennig, S., Cacchi, C., Braunschweig, T., Knüchel-Clarke, R., Jonigk, D., Werlein, C., Bülow, R. D., Dahl, E., von Stillfried, S. & Boor, P. Multisystemic Cellular Tropism of SARS-CoV-2 in Autopsies of COVID-19 Patients. Cells 10, 1900 (2021).
1.
Guarino, M., Cossiga, V., Esposito, I., Furno, A. & Morisco, F. Effectiveness of SARS-CoV-2 vaccination in liver transplanted patients: The debate is open! Journal of Hepatology 76, 237–239 (2022).
1.
von Stillfried, S., Villwock, S., Bülow, R. D., Djudjaj, S., Buhl, E. M., Maurer, A., Ortiz-Brüchle, N., Celec, P., Klinkhammer, B. M., Wong, D. W. L., Cacchi, C., Braunschweig, T., Knüchel-Clarke, R., Dahl, E. & Boor, P. SARS-CoV-2 RNA screening in routine pathology specimens. Microbial Biotechnology 14, 1627–1641 (2021).
1.
Nörz, D., Pfefferle, S., Grunwald, M., Fischer, N., Aepfelbacher, M. & Lütgehetmann, M. Modifying a Diagnostic SARS-CoV-2 Spike PCR to Turn a Del69/70 Dropout into a Discriminatory On-Target Assay. The Journal of Molecular Diagnostics 23, 777–778 (2021).
1.
Tampe, D., Hakroush, S., Bösherz, M.-S., Franz, J., Hofmann-Winkler, H., Pöhlmann, S., Kluge, S., Moerer, O., Stadelmann, C., Ströbel, P., Winkler, M. S. & Tampe, B. Urinary Levels of SARS-CoV-2 Nucleocapsid Protein Associate With Risk of AKI and COVID-19 Severity: A Single-Center Observational Study. Frontiers in Medicine 8, (2021).
1.
Schröder, A. S., Edler, C., Ondruschka, B., Püschel, K., Schädler, J., Heinemann, A., Heinrich, F., Lütgehetmann, M., Pfefferle, S., Aepfelbacher, M., Fitzek, A. & Sperhake, J.-P. The handling of SARS-CoV-2 associated deaths - infectivity of the body. Forensic Sci Med Pathol 17, 411–418 (2021).
1.
Althaus, K., Möller, P., Uzun, G., Singh, A., Beck, A., Bettag, M., Bösmüller, H., Guthoff, M., Dorn, F., Petzold, G. C., Henkes, H., Heyne, N., Jumaa, H., Kreiser, K., Limpach, C., Luz, B., Maschke, M., Müller, J. A., Münch, J., Nagel, S., Pötzsch, B., Müller, J., Schlegel, C., Viardot, A., Bäzner, H., Wolf, M., Pelzl, L., Warm, V., Willinek, W. A., Steiner, J., Schneiderhan-Marra, N., Vollherbst, D., Sachs, U. J., Fend, F. & Bakchoul, T. Antibody-mediated procoagulant platelets in SARS-CoV-2-vaccination associated immune thrombotic thrombocytopenia. Haematologica 106, 2170–2179 (2021).
1.
Bayyoud, T., Iftner, A., Iftner, T., Bartz-Schmidt, K. U., Ziemssen, F., Bösmüller, H., Fend, F., Rohrbach, J. M., Ueffing, M., Schindler, M. & Thaler, S. Severe acute respiratory Syndrome-Coronavirus-2: Can it be detected in the retina? PLOS ONE 16, e0251682 (2021).
1.
Klein, A., Langenwalder, F., Heinrich, F., Meißner, K., Schröder, A. S., Püschel, K., Ondruschka, B., Lütgehetmann, M. & Heinemann, A. SARS-CoV‑2-Zufallsentdeckungen bei Hamburger Todesfällen: ein epidemiologisches Monitoring während des dynamischen Infektionsgeschehens im Frühjahr 2020. Rechtsmedizin 31, 427–433 (2021).
2020
1.
Subbarayan, K., Ulagappan, K., Wickenhauser, C. & Seliger, B. Expression and Clinical Significance of SARS-CoV-2 Human Targets in Neoplastic and Non-Neoplastic Lung Tissues. Current Cancer Drug Targets 21, 428–442 (2020).
1.
Püschel, K., Frenkel, A., Mull, G., Birkholz, H. & Hengfoss, C. COVID-19-Prävention: Einsatz von Fieberkameras zum Schutz vor COVID-19. der kriminalist 11–2020, (2020).
1.
Kommoss, F. K. F., Schwab, C., Tavernar, L., Schreck, J., Wagner, W. L., Merle, U., Jonigk, D., Schirmacher, P. & Longerich, T. The Pathology of Severe COVID-19-Related Lung Damage. Dtsch Arztebl Int 117, 500–506 (2020).
1.
Lauermann, P., Storch, M., Weig, M., Tampe, B., Winkler, M., Hoerauf, H., Feltgen, N. & Hakroush, S. There is no intraocular affection on a SARS-CoV-2 – Infected ocular surface. American Journal of Ophthalmology Case Reports 20, 100884 (2020).
1.
Cantuti-Castelvetri, L., Ojha, R., Pedro, L. D., Djannatian, M., Franz, J., Kuivanen, S., van der Meer, F., Kallio, K., Kaya, T., Anastasina, M., Smura, T., Levanov, L., Szirovicza, L., Tobi, A., Kallio-Kokko, H., Österlund, P., Joensuu, M., Meunier, F. A., Butcher, S. J., Winkler, M. S., Mollenhauer, B., Helenius, A., Gokce, O., Teesalu, T., Hepojoki, J., Vapalahti, O., Stadelmann, C., Balistreri, G. & Simons, M. Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity. Science 370, 856–860 (2020).
1.
Bojkova, D., Wagner, J. U. G., Shumliakivska, M., Aslan, G. S., Saleem, U., Hansen, A., Luxán, G., Günther, S., Pham, M. D., Krishnan, J., Harter, P. N., Ermel, U. H., Frangakis, A. S., Milting, H., Zeiher, A. M., Klingel, K., Cinatl, J., Dendorfer, A., Eschenhagen, T., Tschöpe, C., Ciesek, S. & Dimmeler, S. SARS-CoV-2 infects and induces cytotoxic effects in human cardiomyocytes. Cardiovascular Research 116, 2207–2215 (2020).
1.
Boor, P. & Hartmann, A. Bericht zur Late-Breaking Session Pathologie und COVID-19. Pathologe 41, 96–98 (2020).
1.
Hüppe, D., Niederau, C., Serfert, Y., Hartmann, H., Wedemeyer, H. & Dhc-R, F. D. Versorgungsprobleme von Patienten mit chronischer Hepatitis C während der COVID-19-Pandemie und der Lockdown-Verordnungen. Z Gastroenterol 58, 1182–1185 (2020).
1.
Matschke, J., Lütgehetmann, M., Hagel, C., Sperhake, J. P., Schröder, A. S., Edler, C., Mushumba, H., Fitzek, A., Allweiss, L., Dandri, M., Dottermusch, M., Heinemann, A., Pfefferle, S., Schwabenland, M., Sumner Magruder, D., Bonn, S., Prinz, M., Gerloff, C., Püschel, K., Krasemann, S., Aepfelbacher, M. & Glatzel, M. Neuropathology of patients with COVID-19 in Germany: a post-mortem case series. The Lancet Neurology 19, 919–929 (2020).
1.
Lang, P., Eichholz, T., Bakchoul, T., Streiter, M., Petrasch, M., Bösmüller, H., Klein, R., Rabsteyn, A., Lang, A.-M., Adams, C., Klingel, K., Gessner, M., Rosenberger, P., Ruef, P. & Handgretinger, R. Defibrotide for the Treatment of Pediatric Inflammatory Multisystem Syndrome Temporally Associated With Severe Acute Respiratory Syndrome Coronavirus 2 Infection in 2 Pediatric Patients. Journal of the Pediatric Infectious Diseases Society 9, 622–625 (2020).
1.
Lindner, D., Fitzek, A., Bräuninger, H., Aleshcheva, G., Edler, C., Meissner, K., Scherschel, K., Kirchhof, P., Escher, F., Schultheiss, H.-P., Blankenberg, S., Püschel, K. & Westermann, D. Association of Cardiac Infection With SARS-CoV-2 in Confirmed COVID-19 Autopsy Cases. JAMA Cardiology 5, 1281–1285 (2020).
1.
Bojkova, D., Bechtel, M., McLaughlin, K.-M., McGreig, J. E., Klann, K., Bellinghausen, C., Rohde, G., Jonigk, D., Braubach, P., Ciesek, S., Münch, C., Wass, M. N., Michaelis, M. & Cinatl, J. Aprotinin Inhibits SARS-CoV-2 Replication. Cells 9, 2377 (2020).
1.
Trigaux, C., Salla, S., Schroeter, J., Tourtas, T., Thomasen, H., Maier, P., Hellwinkel, O. J. C., Wittmershaus, I., Merz, P. R., Seitz, B., Nölle, B., Schrage, N., Roters, S., Apel, M., Gareiss-Lok, A., Uhlig, C. E., Thaler, S., Raber, F., Kampik, D., Geerling, G. & Menzel-Severing, J. SARS-CoV-2: Impact on, Risk Assessment and Countermeasures in German Eye Banks. Current Eye Research 46, 666–671 (2021).
1.
Gagiannis, D., Steinestel, J., Hackenbroch, C., Schreiner, B., Hannemann, M., Bloch, W., Umathum, V. G., Gebauer, N., Rother, C., Stahl, M., Witte, H. M. & Steinestel, K. Clinical, Serological, and Histopathological Similarities Between Severe COVID-19 and Acute Exacerbation of Connective Tissue Disease-Associated Interstitial Lung Disease (CTD-ILD). Frontiers in Immunology 11, (2020).
1.
Ackermann, M., Verleden, S. E., Kuehnel, M., Haverich, A., Welte, T., Laenger, F., Vanstapel, A., Werlein, C., Stark, H., Tzankov, A., Li, W. W., Li, V. W., Mentzer, S. J. & Jonigk, D. Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19. N Engl J Med 383, 120–128 (2020).
1.
Sperhake, J.-P. Autopsies of COVID-19 deceased? Absolutely! Legal Medicine 47, 101769 (2020).
1.
Schrappe, M., Francois-Kettner, H., Knieps, F., Pfaff, H., Püschel, K. & Glaeske, G. Die Pandemie durch SARS-CoV-2/Covid-19 – der Übergang zur chronischen Phase. Monitor Versorgungsforschung 5, 35–68 (2020).
1.
Kniep, I., Lutter, M., Ron, A., Edler, C., Püschel, K., Ittrich, H., Heller, M. & Heinemann, A. Postmortale Bildgebung der Lunge bei COVID-19-Todesfällen. Radiologe 60, 927–933 (2020).
1.
Nicolai, L., Leunig, A., Brambs, S., Kaiser, R., Weinberger, T., Weigand, M., Muenchhoff, M., Hellmuth, J. C., Ledderose, S., Schulz, H., Scherer, C., Rudelius, M., Zoller, M., Höchter, D., Keppler, O., Teupser, D., Zwißler, B., von Bergwelt-Baildon, M., Kääb, S., Massberg, S., Pekayvaz, K. & Stark, K. Immunothrombotic Dysregulation in COVID-19 Pneumonia Is Associated With Respiratory Failure and Coagulopathy. Circulation 142, 1176–1189 (2020).
1.
Goebels, H., Edler, C., Fitzek, A., Schädler, J., Schröder, A. S., Kniep, I. & Püschel, K. Obduktionen bei COVID-19. Pathologische Veränderungen und Organmanifestationen. Der Klinikarzt 49, 404–408 (2020).
1.
Wiech, T., Sperhake, J.-P., Zipfel, P. F. & Huber, T. B. Nierenpathologische Befunde bei COVID-19-Patienten. Der Klinikarzt 49, 425–428 (2020).
1.
Wagner, W. L., Hellbach, K., Fiedler, M. O., Salg, G. A., Wehrse, E., Ziener, C. H., Merle, U., Eckert, C., Weber, T. F., Stiller, W., Wielpütz, M. O., Dullin, C., Kenngott, H. G., Schlemmer, H.-P., Weigand, M. A., Schirmacher, P., Longerich, T., Kauczor, H.-U., Kommoss, F. K.-F. & Schwab, C. Mikrovaskuläre Veränderungen bei COVID-19. Radiologe 60, 934–942 (2020).
1.
Bösmüller, H., Traxler, S., Bitzer, M., Häberle, H., Raiser, W., Nann, D., Frauenfeld, L., Vogelsberg, A., Klingel, K. & Fend, F. The evolution of pulmonary pathology in fatal COVID-19 disease: an autopsy study with clinical correlation. Virchows Arch 477, 349–357 (2020).
1.
Eckermann, M., Frohn, J., Reichardt, M., Osterhoff, M., Sprung, M., Westermeier, F., Tzankov, A., Werlein, C., Kühnel, M., Jonigk, D. & Salditt, T. 3D virtual pathohistology of lung tissue from Covid-19 patients based on phase contrast X-ray tomography. eLife 9, e60408 (2020).
1.
Heinrich, F., Sperhake, J.-P., Heinemann, A., Mushumba, H., Lennartz, M., Nörz, D., Glatzel, M., Lütgehetmann, M. & Püschel, K. Germany’s first COVID-19 deceased: a 59-year-old man presenting with diffuse alveolar damage due to SARS-CoV-2 infection. Virchows Arch 477, 335–339 (2020).
1.
Braun, F., Lütgehetmann, M., Pfefferle, S., Wong, M. N., Carsten, A., Lindenmeyer, M. T., Nörz, D., Heinrich, F., Meißner, K., Wichmann, D., Kluge, S., Gross, O., Pueschel, K., Schröder, A. S., Edler, C., Aepfelbacher, M., Puelles, V. G. & Huber, T. B. SARS-CoV-2 renal tropism associates with acute kidney injury. The Lancet 396, 597–598 (2020).
1.
Fuest, M., Boor, P., Knuechel, R., DeRegCOVID, F. T., Walter, P. & Salla, S. Postmortem conjunctival and nasopharyngeal swabs in SARS-CoV-2 infected and uninfected patients. Acta Ophthalmologica 99, e615–e617 (2021).
1.
von Stillfried, S., Bülow, R. D., Röhrig, R., Knüchel-Clarke, R., Boor, P. & the, D. Autopsy registry can facilitate COVID-19 research. EMBO Molecular Medicine 12, e12885 (2020).
1.
Wichmann, D., Sperhake, J.-P., Lütgehetmann, M., Steurer, S., Edler, C., Heinemann, A., Heinrich, F., Mushumba, H., Kniep, I., Schröder, A. S., Burdelski, C., de Heer, G., Nierhaus, A., Frings, D., Pfefferle, S., Becker, H., Bredereke-Wiedling, H., de Weerth, A., Paschen, H.-R., Sheikhzadeh-Eggers, S., Stang, A., Schmiedel, S., Bokemeyer, C., Addo, M. M., Aepfelbacher, M., Püschel, K. & Kluge, S. Autopsy Findings and Venous Thromboembolism in Patients With COVID-19. Ann Intern Med 173, 268–277 (2020).
1.
Puelles, V. G., Lütgehetmann, M., Lindenmeyer, M. T., Sperhake, J. P., Wong, M. N., Allweiss, L., Chilla, S., Heinemann, A., Wanner, N., Liu, S., Braun, F., Lu, S., Pfefferle, S., Schröder, A. S., Edler, C., Gross, O., Glatzel, M., Wichmann, D., Wiech, T., Kluge, S., Pueschel, K., Aepfelbacher, M. & Huber, T. B. Multiorgan and Renal Tropism of SARS-CoV-2. N Engl J Med 383, 590–592 (2020).
1.
Leppkes, M., Knopf, J., Naschberger, E., Lindemann, A., Singh, J., Herrmann, I., Stürzl, M., Staats, L., Mahajan, A., Schauer, C., Kremer, A. N., Völkl, S., Amann, K., Evert, K., Falkeis, C., Wehrfritz, A., Rieker, R. J., Hartmann, A., Kremer, A. E., Neurath, M. F., Muñoz, L. E., Schett, G. & Herrmann, M. Vascular occlusion by neutrophil extracellular traps in COVID-19. EBioMedicine 58, 102925 (2020).
1.
Casagrande, M., Fitzek, A., Püschel, K., Aleshcheva, G., Schultheiss, H.-P., Berneking, L., Spitzer, M. S. & Schultheiss, M. Detection of SARS-CoV-2 in Human Retinal Biopsies of Deceased COVID-19 Patients. Ocular Immunology and Inflammation 28, 721–725 (2020).
1.
Edler, C., Schröder, A. S., Aepfelbacher, M., Fitzek, A., Heinemann, A., Heinrich, F., Klein, A., Langenwalder, F., Lütgehetmann, M., Meißner, K., Püschel, K., Schädler, J., Steurer, S., Mushumba, H. & Sperhake, J.-P. Dying with SARS-CoV-2 infection—an autopsy study of the first consecutive 80 cases in Hamburg, Germany. Int J Legal Med 134, 1275–1284 (2020).
1.
Schreck, J., Baretton, G. & Schirmacher, P. Situation der Deutschen Universitätspathologien unter den Einschränkungen der Corona-Pandemie – Auswertung einer ersten repräsentativen Umfrage. Pathologe 41, 400–405 (2020).
1.
Klein, A., Edler, C., Fitzek, A., Fröb, D., Heinemann, A., Meißner, K., Mushumba, H., Püschel, K., Schröder, A. S., Sperhake, J. P., Ishorst-Witte, F., Aepfelbacher, M. & Heinrich, F. Der erste COVID-19-Hotspot in einer Hamburger Senioreneinrichtung: Präventionskonzept, Letalität und Obduktionsbefunde. RECHTSMEDIZIN 30, 325–331 (2020).
1.
Püschel, K. & Sperhake, J. P. Corona deaths in Hamburg, Germany. Int J Legal Med 134, 1267–1269 (2020).
1.
Püschel, K., Kluge, S., Addo, M. M. & Aepfelbacher, M. Von den Toten lernen – neue Erkenntnisse zu Covid-19. Hamburger Ärzteblatt 73, 34–36 (2020).
1.
Fitzek, A., Sperhake, J., Edler, C., Schröder, A. S., Heinemann, A., Heinrich, F., Ron, A., Mushumba, H., Lütgehetmann, M. & Püschel, K. Evidence for systematic autopsies in COVID-19 positive deceased. Rechtsmedizin 30, 184–189 (2020).
1.
Schädler, J., Gerling, M. & Edler, C. Covid-19-Pneumonie und rezidivierende Lungenembolien. Hamburger Ärzteblatt 36–37 (2020). at <https://fis-uke.de/portal/de/publications/covid19pneumonie-und-rezidivierende-lungenembolien(1f102047-835f-464f-a95e-c366a899d7ee).html>
1.
Ramsthaler, F., Heinbuch, S., Schmidt, P. H., Bohle, R. M., Rissland, J., Gärtner, B., Verhoff, M. A., Kettner, M. & Potente, S. Aktuelle Empfehlungen zum Umgang mit dem Verdacht auf COVID-19 in der rechtsmedizinischen Routine. Archiv für Kriminologie 245, (2020).
1.
Ron, A. & Püschel, K. Todesursachen im Zusammenhang mit Infektionen durch SARS-CoV-2. WUNDmanagement (2020). at <https://www.uke.de/dateien/einrichtungen/medizinische-fakult%C3%A4t/forschung/todesursachen_corona-wundmanagement_p%C3%BCschel-2020.pdf>

© 2023 National Autopsy Network

Contact
Imprint