© 2024 Nationales Obduktionsnetzwerk

Publikationen

2024
[1]
Radke J, Meinhardt J, Aschman T, Chua RL, Farztdinov V, Lukassen S, et al. Proteomic and transcriptomic profiling of brainstem, cerebellum and olfactory tissues in early- and late-phase COVID-19. Nat Neurosci 2024;27:409–20. https://doi.org/10.1038/s41593-024-01573-y.
[1]
Windeck S, Allgoewer K, von Stillfried S, Triefenbach L, Nienaber U, Bülow RD, et al. Entwicklung und Fortschritte des Nationalen Obduktionsnetzwerks (NATON). Pathologie 2024. https://doi.org/10.1007/s00292-024-01307-8.
[1]
Mohme M, Schultheiß C, Piffko A, Fitzek A, Paschold L, Thiele B, et al. SARS-CoV-2-associated T-cell infiltration in the central nervous system. Clinical & Translational Immunology 2024;13:e1487. https://doi.org/10.1002/cti2.1487.
[1]
Lahmer T, Weirich G, Porubsky S, Rasch S, Kammerstetter FA, Schustetter C, et al. Postmortem Minimally Invasive Autopsy in Critically Ill COVID-19 Patients at the Bedside: A Proof-of-Concept Study at the ICU. Diagnostics 2024;14:294. https://doi.org/10.3390/diagnostics14030294.
[1]
Lücke J, Böttcher M, Nawrocki M, Meins N, Schnell J, Heinrich F, et al. Obesity and diabetes mellitus are associated with SARS-CoV-2 outcomes without influencing signature genes of extrapulmonary immune compartments at the RNA level. Heliyon 2024;10:e24508. https://doi.org/10.1016/j.heliyon.2024.e24508.
2023
[1]
Tielker JM, Weber JP, Simon ST, Bausewein C, Stiel S, Schneider N. Experiences, challenges and perspectives for ensuring end-of-life patient care: A national online survey with general practitioners in Germany. PLOS ONE 2021;16:e0254056. https://doi.org/10.1371/journal.pone.0254056.
[1]
Lopes S, Sousa AB de, Delalibera M, Namukwaya E, Cohen J, Gomes B. The rise of home death in the COVID-19 pandemic: a population-based study of death certificate data for adults from 32 countries, 2012–2021. EClinicalMedicine 2024;0. https://doi.org/10.1016/j.eclinm.2023.102399.
[1]
Lutter M, Kniep I, Ondruschka B, Heinemann A. Pulmonale Befunde in der postmortalen Computertomographie bei COVID-19-assoziierten Todesfällen. Rechtsmedizin 2023. https://doi.org/10.1007/s00194-023-00667-4.
[1]
Mothes R, Pascual-Reguant A, Koehler R, Liebeskind J, Liebheit A, Bauherr S, et al. Distinct tissue niches direct lung immunopathology via CCL18 and CCL21 in severe COVID-19. Nat Commun 2023;14:791. https://doi.org/10.1038/s41467-023-36333-2.
[1]
Schädler J, Azeke AT, Ondruschka B, Steurer S, Lütgehetmann M, Fitzek A, et al. Concordance between MITS and conventional autopsies for pathological and virological diagnoses. Int J Legal Med 2023. https://doi.org/10.1007/s00414-023-03088-w.
[1]
Azeke AT, Schädler J, Ondruschka B, Steurer S, Möbius D, Fitzek A. Minimally Invasive Tissue Sampling via Post Mortem Ultrasound: A Feasible Tool (Not Only) in Infectious Diseases-A Case Report. Diagnostics (Basel) 2023;13:2643. https://doi.org/10.3390/diagnostics13162643.
[1]
Heinrich F, Mertz KD, Glatzel M, Beer M, Krasemann S. Using autopsies to dissect COVID-19 pathogenesis. Nat Microbiol 2023:1–9. https://doi.org/10.1038/s41564-023-01488-7.
[1]
Woo MS, Shafiq M, Fitzek A, Dottermusch M, Altmeppen H, Mohammadi B, et al. Vagus nerve inflammation contributes to dysautonomia in COVID-19. Acta Neuropathol 2023;146:387–94. https://doi.org/10.1007/s00401-023-02612-x.
[1]
Stanelle-Bertram S, Beck S, Mounogou NK, Schaumburg B, Stoll F, Al Jawazneh A, et al. CYP19A1 mediates severe SARS-CoV-2 disease outcome in males. Cell Reports Medicine 2023:101152. https://doi.org/10.1016/j.xcrm.2023.101152.
[1]
Lücke J, Heinrich F, Malsy J, Meins N, Schnell J, Böttcher M, et al. Intestinal IL-1β Plays a Role in Protecting against SARS-CoV-2 Infection. The Journal of Immunology 2023:ji2200844. https://doi.org/10.4049/jimmunol.2200844.
[1]
Kolabas ZI, Kuemmerle LB, Perneczky R, Förstera B, Ulukaya S, Ali M, et al. Distinct molecular profiles of skull bone marrow in health and neurological disorders. Cell 2023:S0092867423007420. https://doi.org/10.1016/j.cell.2023.07.009.
[1]
Mieling R, Neidhardt M, Latus S, Stapper C, Gerlach S, Kniep I, et al. Collaborative Robotic Biopsy with Trajectory Guidance and Needle Tip Force Feedback. 2023 IEEE International Conference on Robotics and Automation (ICRA), 2023, p. 6893–900. https://doi.org/10.1109/ICRA48891.2023.10161377.
[1]
Schädler J, Lütgehetmann M, Schröder AS, Edler C, Püschel K, Ondruschka B, et al. Pilot study in Hamburg on the prevalence of SARS-CoV-2 infections and pandemic survey in the German funeral industry. Forensic Sci Med Pathol 2023. https://doi.org/10.1007/s12024-023-00661-y.
[1]
Aschman T, Wyler E, Baum O, Hentschel A, Legler F, Preusse C, et al. Post-COVID syndrome is associated with capillary alterations, macrophage infiltration and distinct transcriptomic signatures in skeletal muscles 2023. https://doi.org/10.1101/2023.02.15.23285584.
[1]
Gagiannis D, Hackenbroch C, Bloch W, Zech F, Kirchhoff F, Djudjaj S, et al. Clinical, Imaging, and Histopathological Features of Pulmonary Sequelae Following Mild COVID-19. Am J Respir Crit Care Med 2023. https://doi.org/10.1164/rccm.202302-0285LE.
[1]
Bräutigam K, Reinhard S, Wartenberg M, Forster S, Greif K, Granai M, et al. Comprehensive analysis of SARS-CoV-2 receptor proteins in human respiratory tissues identifies alveolar macrophages as potential virus entry site. Histopathology 2023;82:846–59. https://doi.org/10.1111/his.14871.
[1]
Granai M, Warm V, Vogelsberg A, Milla J, Greif K, Vogel U, et al. Impact of P-selectin-PSGL-1 Axis on Platelet-Endothelium-Leucocyte Interactions in Fatal COVID-19. Lab Invest 2023:100179. https://doi.org/10.1016/j.labinv.2023.100179.
[1]
Heinrich F, Huter T, Mertens S, Lange P, Vering J, Heinemann A, et al. New Postmortem Perspective on Emerging SARS-CoV-2 Variants of Concern, Germany. Emerg Infect Dis 2023;29:652–6. https://doi.org/10.3201/eid2903.221297.
[1]
Lücke J, Nawrocki M, Schnell J, Meins N, Heinrich F, Zhang T, et al. TNFα aggravates detrimental effects of SARS-CoV-2 infection in the liver. Front Immunol 2023;14:1151937. https://doi.org/10.3389/fimmu.2023.1151937.
2022
[1]
Werlein C, Ackermann M, Stark H, Shah HR, Tzankov A, Haslbauer JD, et al. Inflammation and vascular remodeling in COVID-19 hearts. Angiogenesis 2023;26:233–48. https://doi.org/10.1007/s10456-022-09860-7.
[1]
Gaede K, Heidemann J, Goebels H-L, Heinemann A, Püschel K, Ondruschka B. Pandemic Preparedness bei der Obduktion? Potentiale und Grenzen des IfSG. MedR 2022;40:892–901. https://doi.org/10.1007/s00350-022-6331-6.
[1]
Paparoupa M, Schröder AS, Braunsteiner J, Addo MM, Lütgehetmann M, Roedl K, et al. The Effects of SARS-CoV-2 Virus Type and of Vaccination Status on Causes of Death Over the Course of the COVID-19 Pandemic. Dtsch Arztebl Int 2022:607–8.
[1]
Ackermann M, Jonigk DD. Microvascular placental alterations in maternal COVID-19. Am J Obstet Gynecol 2022;226:135–6. https://doi.org/10.1016/j.ajog.2021.06.098.
[1]
Ackermann M, Tafforeau P, Wagner WL, Walsh CL, Werlein C, Kühnel MP, et al. The Bronchial Circulation in COVID-19 Pneumonia. Am J Respir Crit Care Med 2022;205:121–5. https://doi.org/10.1164/rccm.202103-0594IM.
[1]
Ameratunga R, Woon S-T, Sheppard MN, Garland J, Ondruschka B, Wong CX, et al. First Identified Case of Fatal Fulminant Necrotizing Eosinophilic Myocarditis Following the Initial Dose of the Pfizer-BioNTech mRNA COVID-19 Vaccine (BNT162b2, Comirnaty): an Extremely Rare Idiosyncratic Hypersensitivity Reaction. J Clin Immunol 2022;42:441–7. https://doi.org/10.1007/s10875-021-01187-0.
[1]
Aschman T, Mothes R, Heppner FL, Radbruch H. What SARS-CoV-2 does to our brains. Immunity 2022;55:1159–72. https://doi.org/10.1016/j.immuni.2022.06.013.
[1]
Brandner JM, Boor P, Borcherding L, Edler C, Gerber S, Heinemann A, et al. Contamination of personal protective equipment during COVID-19 autopsies. Virchows Arch 2022;480:519–28. https://doi.org/10.1007/s00428-021-03263-7.
[1]
Bräuninger H, Stoffers B, Fitzek ADE, Meißner K, Aleshcheva G, Schweizer M, et al. Cardiac SARS-CoV-2 infection is associated with pro-inflammatory transcriptomic alterations within the heart. Cardiovasc Res 2022;118:542–55. https://doi.org/10.1093/cvr/cvab322.
[1]
Casagrande M, Fitzek A, Spitzer M, Püschel K, Glatzel M, Krasemann S, et al. Detection of SARS-CoV-2 genomic and subgenomic RNA in retina and optic nerve of patients with COVID-19. Br J Ophthalmol 2022;106:1313–7. https://doi.org/10.1136/bjophthalmol-2020-318618.
[1]
Georg P, Astaburuaga-García R, Bonaguro L, Brumhard S, Michalick L, Lippert LJ, et al. Complement activation induces excessive T cell cytotoxicity in severe COVID-19. Cell 2022;185:493-512.e25. https://doi.org/10.1016/j.cell.2021.12.040.
[1]
Heinrich F, Roedl K, Jarczak D, Goebels H-L, Heinemann A, Schäfer U, et al. New Insights in the Occurrence of Venous Thromboembolism in Critically Ill Patients with COVID-19-A Large Postmortem and Clinical Analysis. Viruses 2022;14:811. https://doi.org/10.3390/v14040811.
[1]
Gagiannis D, Umathum VG, Bloch W, Rother C, Stahl M, Witte HM, et al. Antemortem vs Postmortem Histopathologic and Ultrastructural Findings in Paired Transbronchial Biopsy Specimens and Lung Autopsy Samples From Three Patients With Confirmed SARS-CoV-2. American Journal of Clinical Pathology 2022;157:54–63. https://doi.org/10.1093/ajcp/aqab087.
[1]
Hirschbühl K, Schaller T, Märkl B, Claus R, Sipos E, Rentschler L, et al. High viral loads: what drives fatal cases of COVID-19 in vaccinees? – an autopsy study. Mod Pathol 2022;35:1013–21. https://doi.org/10.1038/s41379-022-01069-9.
[1]
Neidhardt M, Gerlach S, Mieling R, Laves M-H, Weiß T, Gromniak M, et al. Robotic Tissue Sampling for Safe Post-Mortem Biopsy in Infectious Corpses. IEEE Transactions on Medical Robotics and Bionics 2022;4:94–105. https://doi.org/10.1109/TMRB.2022.3146440.
[1]
Heinrich F, Romich C, Zimmermann T, Kniep I, Fitzek A, Steurer S, et al. Dying of VOC-202012/01 — multimodal investigations in a death case of the SARS-CoV-2 variant. Int J Legal Med 2022;136:193–202. https://doi.org/10.1007/s00414-021-02618-8.
[1]
Heinrich F, Schröder AS, Gerberding A-L, Gerling M, Langenwalder F, Lange P, et al. Postmortem Antigen-Detecting Rapid Diagnostic Tests to Predict Infectivity of SARS-CoV-2-Associated Deaths. Emerg Infect Dis 2022;28:244–7. https://doi.org/10.3201/eid2801.211749.
[1]
Jansen J, Reimer KC, Nagai JS, Varghese FS, Overheul GJ, de Beer M, et al. SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids. Cell Stem Cell 2022;29:217-231.e8. https://doi.org/10.1016/j.stem.2021.12.010.
[1]
Jonigk D, Werlein C, Acker T, Aepfelbacher M, Amann KU, Baretton G, et al. Organ manifestations of COVID-19: what have we learned so far (not only) from autopsies? Virchows Arch 2022;481:139–59. https://doi.org/10.1007/s00428-022-03319-2.
[1]
Kamp JC, Neubert L, Ackermann M, Stark H, Werlein C, Fuge J, et al. Time-Dependent Molecular Motifs of Pulmonary Fibrogenesis in COVID-19. Int J Mol Sci 2022;23:1583. https://doi.org/10.3390/ijms23031583.
[1]
Krasemann S, Dittmayer C, von Stillfried S, Meinhardt J, Heinrich F, Hartmann K, et al. Assessing and improving the validity of COVID-19 autopsy studies – A multicentre approach to establish essential standards for immunohistochemical and ultrastructural analyses. EBioMedicine 2022;83:104193. https://doi.org/10.1016/j.ebiom.2022.104193.
[1]
Pomara C, Salerno M, Miani A, Piscitelli P. Autopsies in COVID-related deaths: The need for following the model of German COVID-19 autopsy registry. Lancet Reg Health Eur 2022;17:100392. https://doi.org/10.1016/j.lanepe.2022.100392.
[1]
von Stillfried S, Bülow RD, Röhrig R, Boor P, German Registry of COVID-19 Autopsies (DeRegCOVID), DeRegCOVID Collaborators. First report from the German COVID-19 autopsy registry. Lancet Reg Health Eur 2022;15:100330. https://doi.org/10.1016/j.lanepe.2022.100330.
[1]
von Stillfried S, Bülow RD, Röhrig R, Meybohm P, Boor P, German Registry of COVID-19 Autopsies (DeRegCOVID), DeRegCOVID Collaborators#. Intracranial hemorrhage in COVID-19 patients during extracorporeal membrane oxygenation for acute respiratory failure: a nationwide register study report. Crit Care 2022;26:83. https://doi.org/10.1186/s13054-022-03945-x.
[1]
von Stillfried S, Freeborn B, Windeck S, Boor P. Update zur kooperativen autopsiebasierten Forschung in der deutschen Pathologie, Neuropathologie und Gerichtsmedizin. Pathologie (Heidelb) 2022;43:101–5. https://doi.org/10.1007/s00292-022-01117-w.
[1]
Voigtlaender M, Edler C, Gerling M, Schädler J, Ondruschka B, Schröder AS, et al. Thromboembolic events in deceased patients with proven SARS-CoV-2 infection: Frequency, characteristics and risk factors. Thromb Res 2022;218:171–6. https://doi.org/10.1016/j.thromres.2022.08.021.
[1]
Zickler M, Stanelle-Bertram S, Ehret S, Heinrich F, Lange P, Schaumburg B, et al. Replication of SARS-CoV-2 in adipose tissue determines organ and systemic lipid metabolism in hamsters and humans. Cell Metab 2022;34:1–2. https://doi.org/10.1016/j.cmet.2021.12.002.
[1]
Wanner N, Andrieux G, Badia-I-Mompel P, Edler C, Pfefferle S, Lindenmeyer MT, et al. Molecular consequences of SARS-CoV-2 liver tropism. Nat Metab 2022;4:310–9. https://doi.org/10.1038/s42255-022-00552-6.
2021
[1]
Reichardt M, Moller Jensen P, Andersen Dahl V, Bjorholm Dahl A, Ackermann M, Shah H, et al. 3D virtual histopathology of cardiac tissue from Covid-19 patients based on phase-contrast X-ray tomography. ELife 2021;10:e71359. https://doi.org/10.7554/eLife.71359.
[1]
Heinrich F, Meißner K, Langenwalder F, Püschel K, Nörz D, Hoffmann A, et al. Postmortem Stability of SARS-CoV-2 in Nasopharyngeal Mucosa – Volume 27, Number 1—January 2021 – Emerging Infectious Diseases journal – CDC 2021. https://doi.org/10.3201/eid2701.203112.
[1]
Zack F, Nigbur S, Derani H, Boy D, Port A, Büttner A. Erste Ergebnisse der Obduktionen der im Zusammenhang mit den SARS-CoV-2-Infektionen Verstorbenen aus der Unimedizin Rostock. Ärztebl Meckl-Vorpom 2021;31:125–8.
[1]
Verhoff M, Püschel K, Ondruschka B. SARS-CoV-2: Was bei der Leichenschau infizierter Verstorbener zu beachten ist. MMW Fortschr Med 2021:56–8.
[1]
Püschel K, Goebels H, Ondruschka B, Heinrich F, Bräuninger H, Lindner D, et al. Kardiopathologische Befunde bei COVID-19-Sterbefällen 2021.
[1]
Wendisch D, Dietrich O, Mari T, von Stillfried S, Ibarra IL, Mittermaier M, et al. SARS-CoV-2 infection triggers profibrotic macrophage responses and lung fibrosis. Cell 2021;184:6243-6261.e27. https://doi.org/10.1016/j.cell.2021.11.033.
[1]
Walsh CL, Tafforeau P, Wagner WL, Jafree DJ, Bellier A, Werlein C, et al. Imaging intact human organs with local resolution of cellular structures using hierarchical phase-contrast tomography. Nat Methods 2021;18:1532–41. https://doi.org/10.1038/s41592-021-01317-x.
[1]
van Rüth V, König H-H, Bertram F, Schmiedel P, Ondruschka B, Püschel K, et al. Determinants of health-related quality of life among homeless individuals during the COVID-19 pandemic. Public Health 2021;194:60–6. https://doi.org/10.1016/j.puhe.2021.02.026.
[1]
Verhoff M, Püschel K, Ondruschka B. Über die Ansteckungsgefahr beim Umgang mit SARS-CoV-2-positiven Leichen. Bestattungskultur 2021:24–8.
[1]
Witkowski M, Tizian C, Ferreira-Gomes M, Niemeyer D, Jones TC, Heinrich F, et al. Untimely TGFβ responses in COVID-19 limit antiviral functions of NK cells. Nature 2021;600:295–301. https://doi.org/10.1038/s41586-021-04142-6.
[1]
von Stillfried S, Boor P, DeRegCOVID und DEFEAT PANDEMIcs. Entwicklung eines kooperativen Obduktionsnetzwerks aus Pathologie, Neuropathologie und Rechtsmedizin. Pathologe 2021;42:129–34. https://doi.org/10.1007/s00292-021-01004-w.
[1]
Wenzel J, Lampe J, Müller-Fielitz H, Schuster R, Zille M, Müller K, et al. The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells. Nat Neurosci 2021;24:1522–33. https://doi.org/10.1038/s41593-021-00926-1.
[1]
Heinrich F, Nentwich MF, Bibiza-Freiwald E, Nörz D, Roedl K, Christner M, et al. SARS-CoV-2 Blood RNA Load Predicts Outcome in Critically Ill COVID-19 Patients. Open Forum Infectious Diseases 2021;8:ofab509. https://doi.org/10.1093/ofid/ofab509.
[1]
Ondruschka B, Püschel K, Lange P, Becker I, Rieger-Ndakorerwa G, Schröder AS. SARS-CoV-2-assoziierte Hamburger Sterbefälle in der zweiten Pandemiewelle – Vergleich der bekannt gewordenen Todesfälle in den Gesundheitsämtern und der Rechtsmedizin. Archiv für Kriminologie 2021;248:180–7.
[1]
Michel P, Savinsky G, Ondruschka B, Czinczoll I. Folgen einer Reanimation in Zeiten der Pandemie. Hamburger Ärzteblatt 2021;2021:28–30.
[1]
Nörz D, Grunwald M, Olearo F, Fischer N, Aepfelbacher M, Pfefferle S, et al. Evaluation of a fully automated high-throughput SARS-CoV-2 multiplex qPCR assay with built-in screening functionality for del-HV69/70- and N501Y variants such as B.1.1.7. Journal of Clinical Virology 2021;141:104894. https://doi.org/10.1016/j.jcv.2021.104894.
[1]
Simnica D, Schultheiß C, Mohme M, Paschold L, Willscher E, Fitzek A, et al. Landscape of T-cell repertoires with public COVID-19-associated T-cell receptors in pre-pandemic risk cohorts. Clinical & Translational Immunology 2021;10:e1340. https://doi.org/10.1002/cti2.1340.
[1]
Berezowska S, Boor P, Jonigk D, Tischler V. Update Thoraxpathologie 2021 – Bericht der Arbeitsgemeinschaft. Pathologe 2021;42:199–202. https://doi.org/10.1007/s00292-021-00991-0.
[1]
Lehmann M, Allers K, Heldt C, Meinhardt J, Schmidt F, Rodriguez-Sillke Y, et al. Human small intestinal infection by SARS-CoV-2 is characterized by a mucosal infiltration with activated CD8+ T cells. Mucosal Immunology 2021;14:1381–92. https://doi.org/10.1038/s41385-021-00437-z.
[1]
Menger J, Apostolidou S, Edler C, Kniep I, Kobbe R, Singer D, et al. Fatal outcome of SARS-CoV-2 infection (B1.1.7) in a 4-year-old child. Int J Legal Med 2022;136:189–92. https://doi.org/10.1007/s00414-021-02687-9.
[1]
Schwabenland M, Salié H, Tanevski J, Killmer S, Lago MS, Schlaak AE, et al. Deep spatial profiling of human COVID-19 brains reveals neuroinflammation with distinct microanatomical microglia-T-cell interactions. Immunity 2021;54:1594-1610.e11. https://doi.org/10.1016/j.immuni.2021.06.002.
[1]
Edler C, Klein A, Schröder AS, Sperhake J-P, Ondruschka B. Deaths associated with newly launched SARS-CoV-2 vaccination (Comirnaty®). Legal Medicine 2021;51:101895. https://doi.org/10.1016/j.legalmed.2021.101895.
[1]
Gerlach S, Neidhardt M, Weiß T, Laves M-H, Stapper C, Gromniak M, et al. Needle insertion planning for obstacle avoidance in robotic biopsy. Current Directions in Biomedical Engineering 2021;7:779–82. https://doi.org/10.1515/cdbme-2021-2199.
[1]
Elezkurtaj S, Greuel S, Ihlow J, Michaelis EG, Bischoff P, Kunze CA, et al. Causes of death and comorbidities in hospitalized patients with COVID-19. Sci Rep 2021;11:4263. https://doi.org/10.1038/s41598-021-82862-5.
[1]
O’Hare M, Amarnani D, Whitmore HAB, An M, Marino C, Ramos L, et al. Targeting Runt-Related Transcription Factor 1 Prevents Pulmonary Fibrosis and Reduces Expression of Severe Acute Respiratory Syndrome Coronavirus 2 Host Mediators. The American Journal of Pathology 2021;191:1193–208. https://doi.org/10.1016/j.ajpath.2021.04.006.
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Gromniak M, Neidhardt M, Heinemann A, Püschel K, Schlaefer A. Needle placement accuracy in CT-guided robotic post mortem biopsy. Current Directions in Biomedical Engineering 2020;6. https://doi.org/10.1515/cdbme-2020-0031.
[1]
Aschman T, Schneider J, Greuel S, Meinhardt J, Streit S, Goebel H-H, et al. Association Between SARS-CoV-2 Infection and Immune-Mediated Myopathy in Patients Who Have Died. JAMA Neurology 2021;78:948–60. https://doi.org/10.1001/jamaneurol.2021.2004.
[1]
Kruse JM, Zickler D, Lüdemann WM, Piper SK, Gotthardt I, Ihlow J, et al. Evidence for a thromboembolic pathogenesis of lung cavitations in severely ill COVID-19 patients. Sci Rep 2021;11:16039. https://doi.org/10.1038/s41598-021-95694-0.
[1]
Dittmayer C, Meinhardt J, Radbruch H, Radke J, Heppner BI, Heppner FL, et al. Using EM data to understand COVID-19 pathophysiology – Authors’ reply. The Lancet 2021;397:197–8. https://doi.org/10.1016/S0140-6736(21)00032-5.
[1]
Ihlow J, Michaelis E, Greuel S, Heynol V, Lehmann A, Radbruch H, et al. B cell depletion and signs of sepsis-acquired immunodeficiency in bone marrow and spleen of COVID-19 deceased. International Journal of Infectious Diseases 2021;103:628–35. https://doi.org/10.1016/j.ijid.2020.12.078.
[1]
Greuel S, Ihlow J, Dragomir M-P, Streit S, Corman VM, Haberbosch L, et al. COVID-19: Autopsy findings in six patients between 26 and 46 years of age. International Journal of Infectious Diseases 2021;108:274–81. https://doi.org/10.1016/j.ijid.2021.05.069.
[1]
Ihlow J, Seelhoff A, Corman VM, Gruber AD, Dökel S, Meinhardt J, et al. COVID-19: a fatal case of acute liver failure associated with SARS-CoV-2 infection in pre-existing liver cirrhosis. BMC Infectious Diseases 2021;21:901. https://doi.org/10.1186/s12879-021-06605-7.
[1]
Fitzek A, Schädler J, Dietz E, Ron A, Gerling M, Kammal AL, et al. Prospective postmortem evaluation of 735 consecutive SARS-CoV-2-associated death cases. Sci Rep 2021;11:19342. https://doi.org/10.1038/s41598-021-98499-3.
[1]
Swoboda J, Wittschieber D, Sanft J, Kleemann S, Elschner S, Ihle H, et al. Bone marrow haemophagocytosis indicates severe infection with severe acute respiratory syndrome coronavirus 2. Histopathology 2021;78:727–37. https://doi.org/10.1111/his.14281.
[1]
Kaltschmidt B, Fitzek ADE, Schaedler J, Förster C, Kaltschmidt C, Hansen T, et al. Hepatic Vasculopathy and Regenerative Responses of the Liver in Fatal Cases of COVID-19. Clinical Gastroenterology and Hepatology 2021;19:1726-1729.e3. https://doi.org/10.1016/j.cgh.2021.01.044.
[1]
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